CollagenCharacteristicsAtelocollagen and Hydrolyzed Collagen
| Structure | |
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| Molecular Identity | |
| Type 1: C57H91N19O16 1302.5 Da at least 29 kinds of collagen Types |
Single Collagen Molecule : 360k Da |
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| Characteristics |
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| 1. The main component of connective tissue (Main Structural Protein, 70% of Dermis ) 2. Function : large quantities in connective tissue and provides tendons and ligaments with tensile strength and skin with elasticity 3. Medical Use : Cardiac Applications, Cosmetic Surgery, Bone Graft, Tissue Regeneration,Reconstructive Surgical Use, Wound Healing. 4. Main Components : Glycine, Proline, Alanine, Hydroxyproline, Glutamic Acid. (73.5%). 5. Synthesis by Fibroblast, Degradated by collagenase and serine proteases and others. 6. Main Collagen Components of Dermis are Type I, III, and V . 7. Denaturation temperature is 65ºC, |
| Molecular Identity | |
| Atelocollagen : 300k Da Single Collagen Molecule : 360k Da |
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| Aesthetic Use | |
| Hydrolized Collagen, Atelocollagen | |
| 1. Moisturizing : suppress the TEWL and increase in St.corneum water content, and improve the dermal HA content. 2. Volume Effect : Collagen Volume Itself and Source of Synthesis of Collagen.Regeneration and Wound Healing 3. Tension : Film-Forming 4. Drug delivery carrier : interferon-α , interleukin-2, nerve growth factor, and bone morphogenetic protein, plasmid DNA , antisense oligodeoxynucleotides (ODN) , short interference RNA (siRNA), and micro RNA (miRNA) . and more. Main Type of collagen in the Skin : I, III, and V type of collagen |
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| Comparison | |
 Advantage of Atelocollagen1. There is no Toxicity( Removed Telopeptides, Antigenicity Peptides) 2. Direct Volume and Scaffold Effect 3. Need High Purity |
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| CR Atelocollagen MW 116k Da~205kDa.Skin Permeability : 5.3~6.5% |