Exosomes are a type of Extracellular Vesicles that contain constituents (protein, DNA, and RNA) of the cells that secrete them. They are taken up by distant cells, where they can affect cell function and behavior. UCB-MSC EXOSOME is at leaset twice higher amount of Growth Factors than AD-MSC Exosome and BM-MSC Exosome. Also TGF beta does not find AB-MSC Exosome and BM-MSC Exosome. This Figure shows UCB-MSC Oringin Exosome is strong Collagen Syntheisis Capacity about 7times. Compositions of Exosome are Differ from Origin.
The Extracellular Vesicles: Microvesicles, Apoptotic Blebs, Exosome)
The Contain constituents : nucleic acids, proteins, lipids, cytokines, transcription factor receptors and other bioactive substances
The Size : 40nm~160nm
The Structure : Biological nanoscale spherical lipid bilayer vesicles
The Character : cell-to-cell communication and signalling
The Storage : freezing, freeze-drying and spray-drying.
Service Information to OA
Stem Cell-Derived Extracellular Vesicles for Treating Joint Injury and Osteoarthritis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409698/
The Research Progress of Exosomes in Osteoarthritis, With Particular Emphasis on the Mediating Roles of miRNAs and lncRNAs
https://www.frontiersin.org/articles/10.3389/fphar.2021.685623/full
Intra-articular Injection of MSC-derived Exosomes in Knee Osteoarthritis (ExoOA-1) (ExoOA-1)(Ongoing Study)
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Also Numbers of exosome are Differ from Origin and Cell Condition.
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